Antiproliferative and cytotoxic effects of grape pomace and grape seed extracts on colorectal cancer cell lines
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چکیده
منابع مشابه
Antiproliferative and Apoptotic Effects Triggered by Grape Seed Extract (GSE) versus Epigallocatechin and Procyanidins on Colon Cancer Cell Lines
Grape seed extract has been proven to exert anticancer effects on different tumors. These effects are mainly ascribed to catechin and procyanidin content. Analytical studies demonstrated that grape seed extract composition is complex and it is likely other components could exert biological activities. Using cell count and flow cytometry assays, we evaluated the cytostatic and apoptotic effects ...
متن کاملProcyanidin content of grape seed and pomace, and total anthocyanin content of grape pomace as affected by extrusion processing.
UNLABELLED Grape juice processing by-products, grape seed and pomace are a rich source of procyanidins, compounds that may afford protection against chronic disease. This study was undertaken to identify optimal extrusion conditions to enhance the contents of monomers and dimers at the expense of large molecular weight procyanidin oligomers and polymers in grape seed and pomace. Extrusion varia...
متن کاملCharacterisation of Mediterranean grape pomace seed and skin extracts: polyphenolic content and antioxidant activity.
Grape pomace seeds and skins from different Mediterranean varieties (Grenache [GRE], Syrah [SYR], Carignan [CAR], Mourvèdre [MOU] and Alicante [ALI]) were extracted using water and water/ethanol 70% in order to develop edible extracts (an aqueous extract [EAQ] and a 70% hydro-alcoholic extract [EA70]) for potential use in nutraceutical or cosmetic formulations. In this study, global content (to...
متن کاملAnalysis of Proanthocyanidins in Grape Seed Extracts, Health Foods and Grape Seed Oils
Grape seed extract (GSE) is one of Japan's natural food additives, and is recommended for use as an antioxidant. The component of interest is polyphenol, mainly proanthocyanidins, which are condensed tannins. A vanillin-hydrochloric acid (HCl) assay is specific for flavan-3-ol. The sensitivity of GSE components to the vanillin-HCl assay differed according to the chemical structure. We applied t...
متن کاملRed grape seed extract and its compound resveratrol exert cytotoxic effect to various human cancer lines.
Modern medicinal agents currently available for treatment of cancers are very expensive, toxic, and less effective in treating some of the disease. Thus, one must investigate further in detail the agents derived from natural sources, such as grape seed, for the prevention and treatment of cancer and disease. In recent years interest of researchers has focused on grape seed and nowadays scientis...
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ژورنال
عنوان ژورنال: Food Science & Nutrition
سال: 2019
ISSN: 2048-7177,2048-7177
DOI: 10.1002/fsn3.1150